Beef Research

Celmanax® Research

Effect of Celmanax® Liquid on the Attachment of Cryptosporidium Sporozoites to Bovine Epithelial Cells In-Vitro
RB38
Introduction: Celmanax is a yeast culture product, which has been modified or improved to express more of the metabolites associated with the yeast culture fermentation process. One of the metabolites associated with this production process is Galactosamine. N-acetyl galactosamine has demonstrated an ability to interfere with Cryptosporidium spp ability to attach to intestinal epithilium1. Inhibition of Cryptosporidium sporozoites to adhere and penetrate host cells in the presence of sugars and complex carbohydrates has been reported2. In this study effect of Celmanax on attachment of Cryptosporidium parvum sporozoites to bovine cells is investigated.
Conclusions: The results from this study suggest that Celmanax significantly inhibits the binding of C. parvum sporozoites to bovine epithelial cells in-vitro in a dose-dependent manner.
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